当前位置: 首页 >> 师资队伍 >> 药物化学方向 >> 正文
李悦青讲师
 

 

 

   姓名:李悦青讲师硕士生导师


   办公电话:84986197


   邮箱:angel.laq@163.com 

 

 

 

主要学历及工作简历:
1996.09—2000.07 太原理工大学化工学院学士
2001.09—2003.06 大连理工大学化工学院硕士
2003.09—2006.07 大连理工大学化工学院博士
2006.07—至今大连理工大学制药科学与技术学院讲师/硕导


研究方向:
计算机辅助药物设计
药物化学


研究课题:
1.中央高校基本科研业务费专项:HIV-1 Vif-A3G相互作用的新型抑制剂的设计、合成与活性评价,2011.1-2012.12;


出版著作和论文:
[1] Zhi Cao, Yueqing Li, Shisheng Wang, Xiuhan Guo, Liu Wang, Weijie Zhao*. Total Synthesis of Two Pyrrole Spiroketal Alkaloids: Polleno-pyrroside A and Capparisine B, Synlett, 2015, 26,921-926. (SCI收录,IF2013=2.463)
[2] Jing Xing, Rui Li, Nan Li, Jian Zhang, Yueqing Li, Ping Gong, Dongna Gao, Hui Liu, Yu Zhang*. Anti-inflammatory effect of procyanidin B1 on LPS-treated THP1 cells via interaction with the TLR4–MD-2 heterodimer and p38 MAPK and NF-κB signaling, Molecular and Cellular Biochemistry, 2015,407(1-2):89-95. (SCI收录,IF2013=2.388)
[3] Jiangli Fan*, Wen Sun, Zhenkuan Wang, Xiaojun Peng, Yueqing Li*, and Jianfang Cao. A fluorescent probe for site I binding and sensitive discrimination of HSA from BSA, Chem. Commun. 2014, 50:9573-9576. (SCI收录,IF2013=6.718)
[4] Zhen Li,Yueqing Li, Zhi Cao,Junfeng Gu, Kunji Liu, Weijie Zhao*, Xicheng Wang. Binding Affinity and Efficacy-based Pharmacophore Modeling Studies of Retinoic Acid Receptor alpha Agonists and Virtual Screening for Potential Agonists from NCI database. Med. Chem. Res. 2014,23(8):3916-3926. (SCI收录,IF2012=1.612).
[5] Lei Wang, Yueqing Li, Bohai Jiang and Weijie Zhao*.Determination of the active ingredients in simple recipe ointments by centrifugal partition Chromatography. Anal. Methods, 2014, 6:5245-5249. (SCI收录,IF2013=1.938)
[6] Shisheng Wang, Lijuan Luo, Yueqing Li, Rui Cai, Weijie Zhao*. Qualitative and quantitative analysis of effective components in Fructus Ligustri Lucidi by near infrared spectroscopy. Anal. Methods. 2013,5(12):3045-3049. (SCI收录,IF2013=1.938,他引1次)
[7] Xiaolin Bu, Yueqing Li, Jihong Liu, Debin Zeng, Weijie Zhao. Synthesis of  2-(5-hydroxymethyl-2-formyl-pyrrol-1-yl)propionic acid lactone. Chem. Nat. Compd. 2012, 48(2):194-197. (SCI收录,IF2013=0.5,他引1次)
[8] Daoping Cui, Yueqing Li, Mingming Lian, Feng Yang, Qingwei Meng. Development of a simple and stability-indicating RP-HPLC method for determining olanzapine and related impurities generated in the preparative process. Analyst. 2011, 136(15):3149-3156. (SCI收录,IF2013=3.906,他引2次)
[9] Shiyong Huo,Yueqing Li,Chaoyan Liang,Jihong Liu,Weijie Zhao*. Synthesis of Novel N-carbohydrate-derived Heterocyclic Compounds by nucleophilic substitution reaction of carbohydrate imidazole-1-sulfonates. J Carbohyd. Chem. 2011, 30: 75-84. (SCI收录,IF2013=1.183)
[10] Shiyong Huo,Yueqing Li, Chaoyan Liang, Jihong Liu, Weijie Zhao*. 1-Dibenzylamino -1-deoxy-4,5-O-isopropylidene-β-d-fructopyranose. Acta Cryst. 2011,E67(2):o387. (SCI收录,IF=0.35)
[11] Shiyong Huo,Yueqing Li, Chaoyan Liang, Jihong Liu, Weijie Zhao*. 2,3:4,5-Di-O -isopropylidenefructos-1-yl p-toluene-sulfonate. Acta Cryst. 2010, E66(12):o3097. (SCI收录,IF=0.35)
[12] Xian Zhang, Yueqing Li*, Pingping Chen, Tianjiao Han, Weijie Zhao. Sodium quercetin-8-sulfonate trihydrate. Acta Cryst. 2010, E66, m1036. (SCI收录,IF=0.35)
[13] Qingwei Meng, Yueqing Li, Pingping Chen, Weijie Zhao and Jinzong Yang. 2-(Methoxymethyl)adamantan-2-yl 2-methylacrylate, Acta Cryst. 2009, E65, O2824. (SCI收录,IF=0.35)
[14] 李悦青,黄雅俊,赵伟杰,王希诚. 氮杂茋衍生物靶向虚拟筛选研究,大连理工大学学报,2010,50 (4):486-490.
[15] 曹雪,李悦青,刘季红,赵伟杰. 一种新型的莪术醇衍生物的波谱学分析. 2011, 28(3): 399-406.
[16] 韩天佼,李悦青,谷俊峰,曹志,赵伟杰,王希诚. DPP-Ⅳ抑制剂三维药效团模型构建, 化学工程与技术, 2012,2:53-60.
[17] 蔡蕊,王世盛,李悦青,郭修晗,赵伟杰. 荆条蜂胶化学成分分析. 精细化工,2012,29(2):164-168.
[18] 孟昱,李悦青,蔡蕊,孟庆刚,赵伟杰. 近红外漫反射光谱法快速鉴别药用辅料. 精细化工,2013, 30(10):1143-1148.

工作成果(奖励、专利)
奖励:
1.孟庆伟,张成海、都健,董述祥,李悦青,初永坤、廉明明、李红梅、宋旭阳、宗宇安。《氨磷汀及制剂生产新工艺》,大连市科学技术发明奖,一等奖,2011年。
2.李悦青,董述祥,廉明明,李周民,王世盛,梁敏,孟庆伟,毕文生,王东,杜博。《来氟米特及制剂新产品》,大连市科学技术进步奖,二等奖,2012年。
3.孟庆伟,张成海,都健,董述祥,李悦青,初永坤。《氨磷汀及制剂生产新工艺》,辽宁省科学技术发明奖,二等奖,2013年。
专利:
1.李悦青,赵伟杰,高志刚,张娴,韩天佼.水解天然糖苷类化合物制备苷元的方法,2012.11,中国,ZL.201110000358.0
2.李悦青,赵伟杰,宋其玲,胡勇男.加巴喷丁盐酸盐的合成方法,2013.11,中国,ZL. 201110000739.9
3.李悦青,赵伟杰,宋其玲,张祥芳,李贞.一种具有抗癌活性的黄酮磺酰胺衍生物及其制备方法和应用,2015.4,中国,ZL.201310148997.0
4. 蔡蕊,赵伟杰,李悦青,王世盛,姜博海,高志刚,宋其玲. 近红外光谱法检测蜂胶中黄酮类化合物含量的方法, 2013.11, 中国,ZL.201110000616.5
5.孟庆伟, 崔道平, 李悦青, 廉明明, 姚鸿杰, 刘召鹏. 一种奥氮平有关物质及其制备方法、分析方法, 2013.10, 中国,ZL.201110163535.7
6.孟庆伟, 崔道平, 廉明明, 李悦青, 王亚坤, 姚鸿杰, 刘召鹏. 一种奥氮平有关物质及其制备方法和高效液相色谱分析方法, 2013.10, 中国,ZL.201110163571.3

 

 

上一条:郭修晗讲师
下一条:李广哲副教授
关闭窗口