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罗勇副教授
 

 

 

   姓名:罗勇 副教授 硕士生导师


   办公电话:0411-84986360


   邮箱:yluo@dlut.edu.cn

 

 

 

主要学历及工作简历:
1996.09—2000.06南开大学  化学系 学士
2000.09—2008.01中国科学院大连化学物理研究所  博士
2008.01—2008.11中国科学院大连化学物理研究所  助理研究员(临时)
2008.12—2010.09美国能源部Ames Lab 访问学者
2010.10—至今  大连理工大学  制药科学与技术学院  副教授


主要学术及社会实践:

 


研究方向:
基于微流控芯片的药物活性评价;
基于微流控芯片的药物毒性评价;
基于微流控芯片的药物剂型制备;
基于微流控芯片的药物生物标记物检测;


研究课题:

1,自然科学基金面上项目,21675017,用于ADME研究的集成化器官微流控芯片,2017/1-2020/12,65万,在研,主持

2,科技部重大新药创制,2013ZX09507005001-003-001,抗乳腺癌药物高内涵筛选芯片研制、系统搭建及样机试制,2013/1-2015/12,124.04万,已结题,主持

3,科技部重大仪器专项,2011YQ03012404,基于微流控芯片的体液和细胞样品预处理系统,2011/10-2015/10,270万,已结题,参加

4,辽宁省教育厅一般项目,L2012013,用于药物毒理筛查的微流控芯片仿生血管网络的构建和研究,2012/10-2015/10,3万,已结题,主持

5,农业部公益性农业科技项目,201203088,反刍动物β-激动剂残留规律及监测关键技术研究与示范,2012/1-2016/12,7.5万,在研,参加


出版著作和论文:

 (1) Xiaoguang Lu (*)Chang LvYueyang QuYong LuoBingcheng LinLibin ZhanYi SongZhiwei FanSepsis-induced impairment of neutrophil chemotaxis on a microfluidic chipImmunology Letters, 2016, 17355-60

(2) Fan AnYueyang QuYong Luo(*)Ning FangYang LiuZhigang GaoWeijie ZhaoBingcheng Lin(*)A Laminated Microfluidic Device for Comprehensive Preclinical Testing in the Drug ADME ProcessScientific Reports2016625022

(3) Jiao LiZhuqiang JiaJing KongFuyin ZhangShimeng FangXiaojie LiWuwei LiXuesong YangYong LuoBingcheng LinTingjiao Liu(*)Carcinoma-Associated Fibroblasts Lead the Invasion of Salivary Gland Adenoid Cystic Carcinoma Cells by Creating an Invasive TrackPlos One2016,11(3)e0150247

(4) Kun ZouZhigang GaoQuanfeng DengYong Luo(*)Lijuan Zou(*)Yao LuWeijie ZhaoBingcheng LinPico-molar detection of carcino-embryonic antigen in whole blood using microfluidics and surface-enhanced raman spectroscopyElectrophoresis, 2016, 37, 786-789

(5) Tingting ZhengZhigang GaoYong Luo(*)Xianming Liu(*)Weijie ZhaoBingcheng LinManual-slide-engaged paper chip for parallel SERS-immunoassay measurement of clenbuterol from swine hairElectrophoresis2016373):418-424

(6) Lilu LiuZhaorong XieWenyuan ZhangShimeng FangJing KongDong JinJiao LiXiaojie LiXuesong YangYong LuoBingcheng LinTingjiao Liu(*)Biomimetic tumor-induced angiogenesis and anti-angiogenic therapy in a microfluidic modelRSC Advances20166(42)35248-35256

(7) Dong JinXiaochi MaYong LuoShimeng FangZhaorong XieXiaojie LiDongyuan QiFuyin ZhangJing KongJiao LiBingcheng LinTingjiao Liu(*)Application of a microfluidic-based perivascular tumor model for testing drug sensitivity in head and neck cancers and toxicity in endotheliumRSC Advances20166(35)29598-29607

(8) Fan AnYueyang QuXianming LiuRuntao Zhong(*)Yong Luo(*)Organ-o

n-a-Chip: New Platform for Biological AnalysisAnalytical Chemistry Insights20151039-45

(9) Xu ChenYong Luo(*)Bo Shi(*)Zhigang GaoYuguang DuXianming LiuWeijie ZhaoBingcheng LinDetermination of Beta-agonists in Swine Hair by μFIA and ChemiluminescenceElectrophoresis2015367-8):986-993

(10) Lijun SunYong Luo(*)Zhigang GaoWeijie ZhaoBingcheng LinAn Easy-to-fabricate Thin-film Coating on PDMS Substrate with Super Hydrophilicity and StabilityElectrophoresis2015366):889-892

(11) Bin DouYong Luo(*)Xu ChenBo ShiYuguang DuZhigang GaoWeijie ZhaoBingcheng LinDirect measurement of beta-agonists in swine hair extract in multiplexed mode by surface-enhanced Raman spectroscopy and microfluidic paperElectrophoresis2015363):485-487

(12) Xu ChenYong Luo(*)Bo Shi(*)Xianming LiuZhigang GaoYuguang DuWeijie ZhaoBingcheng LinChemiluminescence diminishment on a paper based analytical device: high throughput determination of b-agonists in swine hairAnalytical Methods2014624):9684-9690

(13) Chang LiuDavid D. Y ChenLirong YuYong Luo(*)Live cell refractometry based on non-SPR microparticle sensorElectrophoresis20133411):1526-1529

(14) Yang LiaoJiangxin SongEn LiYong Luo(*)Yinglong ShenDanping ChenYa Cheng(*)Zhizhan Xu(*)Koji SugiokaKatsumi Midorikawa,Rapid prototyping of three-dimensional microfluidic mixers in glass by femtosecond laser direct writingLab on a Chip2012124):746-749

(15) Yong Luo(#)Chang LiuYueyang QuNing Fang(*)Towards single-cell analysis for pharmacokineticsBioanalysis201244):453-463

(16) Chang LiuYueyang QuYong Luo(*)Ning FangRecent advances in single-molecule detection on micro- and nano-fluidic devicesElectrophoresis20113223):3308-3318

(17) Chang LiuYong LuoE. Jane MaxwellNing FangDavid D. Y. Chen(*)Potential of Two-Dimensional Electro-Fluid-Dynamic Devices for Continuous Purification of Multiple Components from Complex SamplesAnalytical Chemistry20118321):8208-8214

(18) Chang LiuYong LuoNing FangDavid D. Y. Chen(*)Analyte Distribution at Channel Intersections of Electro-Fluid-Dynamic DevicesAnalytical Chemistry2011834):1189-1192

(19) Yong Luo(#)Wei SunChang LiuGufeng WangNing Fang(*)Superlocalization of Single Molecules and Nanoparticles in High-Fidelity Optical Imaging Microfluidic DevicesAnalytical Chemistry20118313):5073-5077

(20) Yong Luo(#)Wei SunYan GuGufeng WangNing Fang(*)Wavelength-Dependent Differential Interference Contrast Microscopy: Multiplexing Detection Using Nonfluorescent NanoparticlesAnalytical Chemistry20108215):6675-6679

(21) Gufeng WangWei SunYong LuoNing Fang(*)Resolving Rotational Motions of Nano-objects in Engineered Environments and Live Cells with Gold Nanorods and Differential Interference Contrast MicroscopyJournal of the American Chemical Society201013246):16417-16422

(22) Chang Liu(#)Yong Luo(#)E. Jane MaxwellNing FangDavid D. Y. Chen(*), Reverse of Mixing Process with a Two-Dimensional Electro-Fluid-Dynamic DeviceAnalytical Chemistry2010826):2182-2185

(23) Yong Luo(#)Jianhua QinBingcheng Lin(*)Methods for pumping fluids on biomedical lab-on-a-chipFrontiers in Bioscience2009143913-3924

(24) Yan GaoYong LuoJianhua QinBingcheng Lin(*)A multichannel electrophoresis microchip platform for rapid chiral selector screeningElectrophoresis2008299):1918-1923

(25) Yong Luo(#)Qingquan ZhangJianhua QinBingcheng Lin(*)Further improvement of hydrostatic pressure sample injection for microchip electrophoresisElectrophoresis20072824):4769-4771

(26) Yan GaoYong LuoJianhua QinBingcheng Lin(*)A multichannel electrophoresis microchip platform for rapid chiral selector screeningthe First Shenyang International Colloquium on Microfluidics2007.10.21-2007.10.24

(27) Yong Luo(#)Dapeng WuShaojiang ZengHongwei GaiZhicheng

LongZheng ShenZhongpeng DaiJianhua QinBingcheng Lin(*)Double-cross

hydrostatic pressure sample injection for chip CE: Variable sample plug volume

and minimum number of electrodesAnalytical Chemistry20067817):6074-6080

(28) Xiaomian ZhouZhongpeng DaiXin LiuYong LuoHui WangBingcheng Lin(*)Modification of a poly(methyl methacrylate) injection-molded microchip and its use for high performance analysis of DNAJournal of Separation Science2005283):225-233

(29) Xiaomian ZhouZhongpeng DaiYong LuoDayu LiuHui WangXiuli MaoBingcheng Lin(*)Microfabrication and performance of poly(methylmethacrylate) microfluidic chip with multi-channelsChemical Journal of Chinese Universities-Chinese2005261):52-54

(30) Dapeng WuYong LuoXiaomian ZhouZhongpeng DaiBingcheng Lin(*)Multilayer poly(vinyl alcohol)-adsorbed coating on poly(dimethylsiloxane) microfluidic chips for biopolymer separationElectrophoresis2005261):211-218

(31) Xiuli MaoYong LuoZhongpeng DaiKeyi WangYuguang DuBingcheng Lin(*)Integrated lectin affinity microfluidic chip for glycoform separationAnalytical Chemistry20047623):6941-6947


 

授权发明专利

 (1) 罗勇,窦斌,高志刚,赵伟杰,林炳承,田中群,一种基于SERS检测瘦肉精类物质的高通量纸质微流控芯片,2016.1.13-2036.1.13,中国,201410214694.9。

(2) 罗勇,郑婷婷,高志刚,赵伟杰,林炳承,田中群,基于SERS检测瘦肉精类物质的开关控制型纸质微流控芯片,2015.10.28-2035.10.28,中国,201410328800.6。

(3) 刘婷娇,金冬,林炳承,罗勇,一种多维多浓度药敏检测微流控芯片,2015.1.14-2025.1.14,中国,201420262631.6。

(4) 秦建华,罗勇,林炳承,一种完全集成于微流控芯片的储液池微泵,2012.8.29-2032.8.29,中国,200710158570.3。

(5) 吴大朋,罗勇,周小棉,戴忠鹏,林炳承,一种细胞差异表达与基因测试复合微流芯片,2008.12.3-2028.12.3,中国,02132799.8。

(6) 周小棉,戴忠鹏,罗勇,林炳承,亲水性聚甲基丙烯酸甲酯芯片材料、芯片及其制备方法,2006.7.26-2026.7.26,中国,200310105076.2。

(7) 戴忠鹏,罗勇,盖宏伟,林炳承,一种带筛孔的塑料微流控芯片的制备方法,2006.2.15-2026.2.15,中国,03111164.5。

(8) 罗勇,林炳承,一种带有毛细管-微流控芯片接口的微流控芯片,2006.1.18-2016.1.18,中国,200420055251.1。

(9) 王刚,许英毅,陈荣达,周小棉,罗勇,戴忠鹏,林炳承,一种电感耦合等离子体检测微流控芯片,2005.6.1-2025.6.1,中国,02130721.0。

(10) 梁爱叶,罗勇,王克夷,杜昱光,林炳承,一种肝素靶酶的筛选方法及其专用多功能微流控芯片,2005.3.30-2025.3.30,中国,02132790.4。

(11) 戴忠鹏,罗勇,林炳承,一种塑料芯片固化用组合模具,2004.5.12-2014.5.12,中国,03213340.5。

(12) 戴忠鹏,周小棉,罗勇,林炳承,分离检测用三通道微流控芯片,2003.12.24-2013.12.24,中国,03311213.4。

(13) 周小棉,罗勇,戴忠鹏,林炳承,聚合酶链反应用芯片分析仪,2003.11.19-2013.11.19,中国,02340742.5。

(14) 周小棉,罗勇,戴忠鹏,林炳承,激光诱导荧光芯片分析仪,2003.10.8-2013.10.8,中国,02340741.7。

(15) 王刚,许英毅,陈荣达,周小棉,罗勇,戴忠鹏,林炳承,一种电感耦合等离子体检测微流控芯片,2003.8.27-2013.8.27,中国,02257346.1。

(16) 罗勇,周小棉,林炳承,一种塑料芯片固化用组合模具,2003.5.21-2013.5.21,中国,02274233.6。

(17) 周小棉,戴忠鹏,罗勇,林炳承,一种微流控芯片,2003.5.21-2013.5.21,中国,02274236.0。

(18) 戴忠鹏,罗勇,林炳承,一种微流控塑料芯片注射成型模具,2003.5.14-2013.5.14,中国,02274234.4。

(19) 周小棉,罗勇,戴忠鹏,林炳承,多通道微流控芯片,2003.3.5-2013.3.5,中国,02353129.0。

(20) 周小棉,罗勇,戴忠鹏,林炳承,微流控芯片,2003.2.19-2013.2.19,中国,02353130.4。

 

其他成果

 (1) Yong Luo,Top 1% of authors,highly cited in the Royal Society of Chemistry journals in 2014,英国, 2014

(2) 林炳承,秦建华,王辉,盖宏伟,王刚,周小棉,毛秀丽,姜雷,梁爱叶,刘大渔,罗勇,龙志成,吴大朋,沈铮,刘欣,刘晓君,钟润涛,於林芬,黄淮青,马波,高雁,解华,李博伟,叶囡楠,张宇,李进,曾绍江,陆瑶,施维维,进样及样品前处理技术,微流控芯片实验室, 杨震 黄海, 科学出版社, pp 67-103, 中国, 2006/7

(3) 罗勇,安凡,曲玥阳,高志刚,赵伟杰,林炳承,田中群,一种基于微流控芯片技术构建的仿生芯片,中国,201510603772.9。

(4) 罗勇,吕畅,路晓光,高志刚,赵伟杰,林炳承,田中群,一种实现白细胞趋化作用的微流控芯片,中国,201410538174.3。

(5) 罗勇,于晓,高志刚,赵伟杰,林炳承,田中群,一种用于瘦肉精类物质检测的高通量微流控芯片,中国,201410200697.7。

(6) 罗勇,孙丽君,赵伟杰,林炳承,田中群,一种实现肝肠循环药物筛选的微流控芯片,中国,201410191283.2。

(7) 秦建华,高雁,罗勇,戴忠鹏,林炳承,用于快速筛选手性选择剂的方法及专用的阵列微流控芯片,中国,200710011920.3。

(8) 罗勇,林炳承,一种免疫分析用微流控芯片及其在免疫分析中的应用,中国,200310105072.4。

(9) 林炳承,刘大渔,钟润涛,戴忠鹏,罗勇,李义海,梅晓丹,一种微流控芯片及其早期诊断系统和应用,中国,03133769.4。

(10) 盖宏伟,於林芬,戴忠鹏,罗勇,马银法,林炳承,一种基于微流控芯片的细胞分选方法及其专用芯片,中国,03133463.6。

 

获得学术奖励

(1) 罗勇(6/6),微流控芯片电泳系统,辽宁省科学技术奖励委员会,科学技术奖励,省部一等奖,2007。(林炳承,秦建华,周小棉,戴忠鹏,姜雷,罗勇)

(2) 罗勇(1/1),基于可调进样量和最小数量电极的双十字静压力芯片电泳进样方法,大连市科学技术协会,大连市自然科学优秀学术论文,市级二等奖,2007。(罗勇)

 

 

 

 

 

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